HAZARD RATES AND RESTRICTED MEAN SURVIVAL TIME
نویسندگان
چکیده
منابع مشابه
Modeling restricted mean survival time under general censoring mechanisms.
Restricted mean survival time (RMST) is often of great clinical interest in practice. Several existing methods involve explicitly projecting out patient-specific survival curves using parameters estimated through Cox regression. However, it would often be preferable to directly model the restricted mean for convenience and to yield more directly interpretable covariate effects. We propose gener...
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For designing, monitoring and analyzing a longitudinal study with an event time as the outcome variable, the restricted mean event time (RMET) is an easily interpretable, clinically meaningful summary of the survival function in the presence of censoring. The RMET is the average of all potential event times measured up to a time point τ, which can be estimated consistently by the area under the...
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BACKGROUND Designs and analyses of clinical trials with a time-to-event outcome almost invariably rely on the hazard ratio to estimate the treatment effect and implicitly, therefore, on the proportional hazards assumption. However, the results of some recent trials indicate that there is no guarantee that the assumption will hold. Here, we describe the use of the restricted mean survival time a...
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ژورنال
عنوان ژورنال: Indonesian Journal of Statistics and Its Applications
سال: 2019
ISSN: 2599-0802
DOI: 10.29244/ijsa.v3i3.520